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Registro Completo |
Biblioteca(s): |
Embrapa Pantanal. |
Data corrente: |
09/03/2000 |
Data da última atualização: |
31/03/2017 |
Autoria: |
LIFSCHITZ, A.; VIRKEL, G.; IMPERIALE, F.; SUTRA, J. F.; GALTIER, P.; LANUSSE, C.; ALVINERIE, M. |
Título: |
Moxidectin in cattle: correlation between plasma and target tissues disposition. |
Ano de publicação: |
1999 |
Fonte/Imprenta: |
Journal Veterinary Pharmacology and Therapeutics, v.22, p.266-273, 1999. |
Idioma: |
Inglês |
Conteúdo: |
The time of parasite exposure to active drug concentrations determines the persistence of the antiparasitic activity of endectocide compounds. This study evaluates the disposition kinetics of moxidectin (MXD) in plasma and in different target tissues folloeing its subcutaneous (s.c.) administration to cattle. Eighteen male, 10-month old Holstein calves weighing 120-140 kg were subcutaneously injected in the shoulder area with a commercially available formulation of MXD (Cydectin 1%, American Cyanamid, Wayne, NJ, USA) at 200 ug/kg. Two treated calves were killed at each of the following times post-treatment: 1, 4, 8, 18, 28, 38, 48, 58 and 68 days. |
Palavras-Chave: |
Parasita; Parasite. |
Thesagro: |
Gado; Plasma. |
Thesaurus Nal: |
cattle; moxidectin. |
Categoria do assunto: |
-- |
Marc: |
LEADER 01347naa a2200265 a 4500 001 1799788 005 2017-03-31 008 1999 bl --- 0-- u #d 100 1 $aLIFSCHITZ, A. 245 $aMoxidectin in cattle$bcorrelation between plasma and target tissues disposition. 260 $c1999 520 $aThe time of parasite exposure to active drug concentrations determines the persistence of the antiparasitic activity of endectocide compounds. This study evaluates the disposition kinetics of moxidectin (MXD) in plasma and in different target tissues folloeing its subcutaneous (s.c.) administration to cattle. Eighteen male, 10-month old Holstein calves weighing 120-140 kg were subcutaneously injected in the shoulder area with a commercially available formulation of MXD (Cydectin 1%, American Cyanamid, Wayne, NJ, USA) at 200 ug/kg. Two treated calves were killed at each of the following times post-treatment: 1, 4, 8, 18, 28, 38, 48, 58 and 68 days. 650 $acattle 650 $amoxidectin 650 $aGado 650 $aPlasma 653 $aParasita 653 $aParasite 700 1 $aVIRKEL, G. 700 1 $aIMPERIALE, F. 700 1 $aSUTRA, J. F. 700 1 $aGALTIER, P. 700 1 $aLANUSSE, C. 700 1 $aALVINERIE, M. 773 $tJournal Veterinary Pharmacology and Therapeutics$gv.22, p.266-273, 1999.
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Embrapa Pantanal (CPAP) |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Amazônia Oriental. Para informações adicionais entre em contato com cpatu.biblioteca@embrapa.br. |
Registro Completo
Biblioteca(s): |
Embrapa Amazônia Oriental. |
Data corrente: |
03/11/2022 |
Data da última atualização: |
12/12/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 2 |
Autoria: |
KAUFFMANN, C. M.; BOARI, A. de J.; SILVA, J. M. F.; BLAWID, R.; NAGATA, T. |
Afiliação: |
CATERYNNE MELO KAUFFMANN, UNIVERSIDADE DE BRASÍLIA; ALESSANDRA DE JESUS BOARI, CPATU; JOÃO MARCOS FAGUNDES SILVA, UNIVERSIDADE DE BRASÍLIA; ROSANA BLAWID, UNIVERSIDADE FEDERAL RURAL DE PERNAMBUCO; TATSUYA NAGATA, UNIVERSIDADE DE BRASÍLIA. |
Título: |
Complete genome sequence of patchouli chlorosis-associated cytorhabdovirus, a new cytorhabdovirus infecting patchouli plants in Brazil. |
Ano de publicação: |
2022 |
Fonte/Imprenta: |
Archives of Virology, v. 167, n. 12, p. 2817-2820, 2022. |
DOI: |
https://doi.org/10.1007/s00705-022-05594-5 |
Idioma: |
Inglês |
Conteúdo: |
A cytorhabdovirus, tentatively named "patchouli chlorosis-associated cytorhabdovirus" (PCaCV), was identified in a patchouli plant, using high-throughput sequencing, and its genome sequence was confirmed by Sanger sequencing. The PCaCV genome consists of 12,913 nucleotides and contains six open reading frames in the order 3'-N-P'-P-P3-M-(G)-L-5'. The glycoprotein gene was found to contain stop codons in the coding frame; hence, this gene is considered defective. PCaCV is most closely related to tomato yellow mottle-associated virus, sharing 61.1% nucleotide sequence identity in the complete genome and 73.9% amino acid sequence identity in the L protein. These data suggest that PCaCV should be considered a new member of the genus Cytorhabdovirus, and the binomial species name "Cytorhabdovirus patchoulii" is proposed. |
Palavras-Chave: |
Patchouli. |
Thesagro: |
Genoma; Vírus. |
Categoria do assunto: |
-- |
Marc: |
LEADER 01523naa a2200217 a 4500 001 2147984 005 2022-12-12 008 2022 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1007/s00705-022-05594-5$2DOI 100 1 $aKAUFFMANN, C. M. 245 $aComplete genome sequence of patchouli chlorosis-associated cytorhabdovirus, a new cytorhabdovirus infecting patchouli plants in Brazil.$h[electronic resource] 260 $c2022 520 $aA cytorhabdovirus, tentatively named "patchouli chlorosis-associated cytorhabdovirus" (PCaCV), was identified in a patchouli plant, using high-throughput sequencing, and its genome sequence was confirmed by Sanger sequencing. The PCaCV genome consists of 12,913 nucleotides and contains six open reading frames in the order 3'-N-P'-P-P3-M-(G)-L-5'. The glycoprotein gene was found to contain stop codons in the coding frame; hence, this gene is considered defective. PCaCV is most closely related to tomato yellow mottle-associated virus, sharing 61.1% nucleotide sequence identity in the complete genome and 73.9% amino acid sequence identity in the L protein. These data suggest that PCaCV should be considered a new member of the genus Cytorhabdovirus, and the binomial species name "Cytorhabdovirus patchoulii" is proposed. 650 $aGenoma 650 $aVírus 653 $aPatchouli 700 1 $aBOARI, A. de J. 700 1 $aSILVA, J. M. F. 700 1 $aBLAWID, R. 700 1 $aNAGATA, T. 773 $tArchives of Virology$gv. 167, n. 12, p. 2817-2820, 2022.
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